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. Author manuscript; available in PMC: 2009 May 19.
Published in final edited form as: Semin Nephrol. 2007 Nov;27(6):609–620. doi: 10.1016/j.semnephrol.2007.09.006

Figure 4.

Figure 4

Figure 4

Figure 4A. Effect of cisplatin on NEFA levels in serum, urine and kidney tissue. Mice were administered saline (control) or cisplatin (20 mg/kg body weight) by a single intraperitoneal injection. NEFA levels were measured at day1, day2, day3 after cisplatin injection in serum, urine, and kidney tissue homogenates as described in Methods. Bars correspond to means ± SE of at least 6 independent experiments under each condition. *p < 0.05, compared with control by unpaired student’s t-test.

Figure 4B Effect of cisplatin and fibrate (WY) on NEFA levels. Wild-type mice were fed with either a regular or WY-containing diet and then were given saline (control and WY groups) or cisplatin (cisplatin and cisplatin + WY groups). NEFA levels were measured at day 3 after cisplatin injection in serum, urine, and kidney tissue homogenates as described in Methods Results are expressed as the means ± SE. †P < 0.05 compared to cisplatin, *P < 0.05, compared with control by unpaired Student’s t-test.