Fig. 3.
Effect of increasing Ang II concentrations on fibronectin production in MES-13 cells as measured by ELISA. In cells cultured in 5.5 mmol/l glucose medium, addition of Ang II at concentrations between 10−8 and 10−5 M resulted in a dose-related increase in fibronectin levels in conditioned medium (P<0.01). Data shown were generated from four separate 72 h culture experiments. a,b,c Superscripts denote significantly different mean fibronectin concentrations (P < 0.05)