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In vitro metabolism of DEN in non-treated and CXB-treated rat hepatic microsomes. The denitrosation rate was measured by the production of nitrites, and the deethylation rate was measured by the production of acetaldehyde in the presence or absence of SKF-525A. Values are presented as mean ± SD. aP < 0.05, vs NT group; cP < 0.05 vs CXB group. Bonferroni test, n = 4 for all groups.
