Table 4.
Analysis of ALDH2 and ADH2 genotypes and risk of esophageal cancer with reference to drinking habits
| Genotypes |
Non-drinker |
Drinker |
|||||
| Cases | Controls | OR1 (95% CI) | Cases | Controls | OR1 (95% CI) | ||
| ALDH2 | |||||||
| G/G | 26 | 42 | 1.00 | 64 | 72 | 1.00 | |
| G/A | 43 | 44 | 1.29 (0.65-2.55) | 46 | 22 | 2.47 (1.27-4.82) | |
| A/A | 27 | 8 | 4.67 (1.63-13.38) | 15 | 3 | 8.63 (2.07-35.95) | |
| G/A+A/A | 70 | 52 | 1.78 (0.94-3.37) | 61 | 25 | 3.08 (1.65-5.78) | |
| ADH2 | |||||||
| A/A | 50 | 53 | 1.00 | 56 | 55 | 1.00 | |
| G/A | 42 | 38 | 1.31 (0.70-2.46) | 54 | 37 | 1.18 (0.64-2.16) | |
| G/G | 4 | 3 | 2.10 (0.35-12.54) | 15 | 5 | 2.90 (0.85-9.90) | |
| G/A+G/G | 46 | 41 | 1.37 (0.74-2.54) | 69 | 42 | 1.36 (0.76-2.43) | |
| ALDH2 | ADH2 | ||||||
| G/G | A/A | 10 | 28 | 1.00 | 34 | 40 | 2.02 (0.79-5.17) |
| G/A+A/A | G/A+G/G | 30 | 27 | 2.84 (1.10-7.31) | 39 | 10 | 8.36 (2.98-23.46) |
1
ORs were adjusted for income.