Figure 5. The structural superposition of the core of the proteins.

The structure of Ureidoglycolate hydrolase (1YQCa_) is in light blue (A), RmlC epimerase (1EPZa_) in magenta (B), Glucose-6-phosphate isomerase (1QXRa_) in blue (C) and 5-keto-4-deoxyuronate isomerase (1XRUa2) in green (D). The substrates are shown as sticks, metals as spheres and the metal binding residues at the active site as lines. Marked structural variations in the region accommodating metal binding residues can be seen.