Table 3.
Blood and Urine Analysis
| IPAH (n=19) | CTEPH (n=15) | LHF-Controls (n=24) | PAH vs CTEPH (p-Values) | PH vs Controls (p-Vlaues) | |
|---|---|---|---|---|---|
| General | |||||
| pro-BNP (<88 ng/L) | 2500 (1874) | 2256 (1505) | 3617 (3501) | 0.97 | 0.224 |
| C-reactive protein (<1 mg/l) | 9.2 (9.5) | 10.4 (10.4) | 16.9 (13.6) | 0.957 | 0.007* |
| Uric Acid (150-300 µmol/L) | 460 (172) | 471 (147) | 488 (178) | 0.762 | 0.79 |
| Creatinine (Cr) (44-80 µmol/L) | 110 (38) | 95 (9) | 114 (33) | 0.228 | 0.209 |
| GFR MDRD (> 60 ml/min/m2)*** | 47 (16) | 51 (11) | 47 (13) | 0.376 | 0.764 |
| Albumin (34-48 g/l) | 44 (10) | 42 (4) | 38 (3) | 0.631 | <0.001** |
| Bone Metabolism | |||||
| Calcium, alb-adj.(2.09-2.54 mmol/L)**** | 2.32 (0.2) | 2.24 (0.1) | 2.19 (0.4) | 0.157 | 0.515 |
| Phosphate (0.87-1.45 mmol/L) | 0.99 (0.2) | 1.02 (0.2) | 1.21 (0.3) | 0.246 | 0.009* |
| Ostase (3.4-9.8 µg/L) | 15.3 (6) | 14.9 (6) | 10.7 (6) | 0.800 | 0.002* |
| PTH (15-65 ng/L) | 88 (71) | 93 (45) | 56 (23) | 0.331 | 0.027* |
| 25-Hydroxy-Vitamin D (10-42 µg/L) | 15 (6) | 15 (8) | 19 (10) | 0.556 | 0.137 |
| Urinary calcium/creatinine ( 0.1-0.5 mmol/mmol) | 0.47 (0.42) | 0.62 (0.64) | 0.30 (0.31) | 0.794 | 0.031* |
| Urinary deoxypyridinoline/creatinine (2.5-5 nmol/mmol) | 7.87 (10.3) | 7.63 (1.98) | 8.64 (4.12) | 0.710 | 0.676 |
Normal values in brackets after parameters. Results given as means (SD).
*
p<0.05
**
p<0.00.
***
Albumin-adjusted serum calcium= calcium (mmol/l)-0.02*[albumin(g/l)-40].
****
GFR (MDRD) [ml/min/1.73m2]= 186*(serum Cr(mg/dl)/0.95)-1.154*(age)-0.203*(0.742 in women).