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Effect of Ang-(1–7) on SHP-1 activity. (A) Graph depicts the effect of Ang-(1–7) (10−7 M) on SHP-1 activity in normal glucose (NG, 5 mM), with or without Ang-(1–7) (10−7 M) or A-779 (10−5 M). *P < 0.05 versus control, **P < 0.05 versus Ang-(1–7); n = 3. (B) SHP- 1 activity in high glucose (HG, 25 mM) is depicted with or without Ang-(1–7) (10−7 M) or A-779 (10−5 M). *P < 0.01 versus control; **P < 0.01 versus Ang-(1–7); n = 5. Results are presented in arbitrary units.
