Table 3.

Adverse Events

Adverse Event	B Vitamins Group	Placebo Group
	N (Percent)
Arthralgia	16 (6.7)	7 (4.1)
Depressed mood	45 (18.8)	20 (11.8)
Depression	16 (6.7)	8 (4.7)
Dyspnoea	18 (7.5)	9 (5.3)
Headache	20 (8.3)	9 (5.3)
Hyperhidrosis	23 (9.6)	7 (4.1)
Joint swelling	17 (7.1)	6 (3.6)
Restlessness	29 (12.1)	14 (8.3)
Upper respiratory tract infection	16 (6.7)	6 (3.6)
Urinary tract infection	16 (6.7)	8 (4.7)
Vision blurred	13 (5.4)	3 (1.8)

Table lists adverse events that occurred in at least 5 percent of participants in either treatment group. In two instances, the differences in occurrence rates between groups approached significance: hyperhidrosis: p-value=.053, and vision blurred: p-value=.072 using Fisher’s Exact test.