Table 3.
fMRI results: effect of family history on APOE ϵ4 carriers
Cluster p (cor) | Cluster size | Voxel p (FDR-cor) | Voxel t | x, y, z (MNI) | VBM t | Location |
---|---|---|---|---|---|---|
<0.001 | 1451 | <0.001 | 6.66 | 42, −50, −22 | −0.34 | Right fusiform |
<0.001 | 5.43 | 34, −20, −20 | 1.89 | Right hippocampus | ||
0.138 | 130 | 0.001 | 4.26 | −32, −26, −14 | 2.01 | Left hippocampus |
0.01 | 290 | 0.002 | 3.99 | −40, −52, −14 | −2.84 | Left fusiform |
This t-contrast tests for voxels in which the −FH, +ϵ4 group exhibits more activity than the +FH, +ϵ4 group. There were no significant results in the reverse contrast. cor, Corrected; FDR-cor, FDR correction for multiple comparisons.