Table 2.

Selected mRNAs associated with ZBP1 in breast-cancer cells

Rank	Transcripts	Gene bank ID	Location of conserved `zipcode' sequences	Scald fold enrichment MTLn3-ZBP1/MTLn3	Biological functions
A1	β-actin	NP_112406	3′ UTR	223.1	Cytoskeleton; cell motility
A2	P21-ARC (subunit 3)	NM_001105933	Coding region	215.0	Actin cytoskeleton regulation
A3	Galectin-3	NP_114020	Absent	194.6	Heterophilic cell adhesion
A4	Endolyn	NM_031812	Coding region	83.9	Cell adhesion; cell proliferation
A5	P16-ARC (subunit 5)	NM_001037767	Absent	60.5	Actin cytoskeleton regulation
A6	Evl (RNB6)	NM_024147	Coding region	42.2	Actin-filament-based movement; cell motility
A7	Actinin α1	NP_112267	Coding region	33.6	Actin cross-linking; actin organization
A8	E-cadherin	NP_112624	3′ UTR	33.1	Cell adhesion
A9	β-catenin	NP_445809	Coding region	26.5	Cell-cell contacts; Wnt signaling
B1	Cyclin D1	NP_741989	Coding region	241.4	Cell proliferation; Wnt signaling
B2	Hepatoma-derived growth factor	NP_446159	3′ UTR	60	Cell proliferation
B3	Cyclin A2	NM_053702	Absent	28.7	Cell proliferation
B4	Anxa1	NP_037036	Absent	48.4	Regulation of cell proliferation
B5	Erv1, growth factor homolog	NP_037354	Coding region	32.7	Cell proliferation
B6	Rcl	NP_598209	Absent	21.9	Cell proliferation; putative Myc-responsive
B7	Cyclin G1	NP_037055	Coding region	21.8	Cytokinesis; mitosis; cell-cycle regulation
B8	Frk (Src-related tyrosine kinase)	NM_024368	Coding region	19.4	Cell differentiation

Microarray experiments and data analyses were performed in the Center for Functional Genomics at the University of Albany. Two categories of 17 transcripts were selected from the microarray results. One category of mRNAs contained transcripts important for cell motility and adhesion (rank A1-A9). The second category of ZBP1-bound mRNAs included those necessary for cell mitosis and growth (rank B1-B8). Location of the conserved `zipcode' sequences within the transcripts is indicated.