Fig. 7.

VK1 metabolism in HLM is inhibited by CYP4F2 antibody. Incubations contained 500 μg of microsomal protein preincubated on ice with antibody for 30 min before initiation with the addition of saturating concentrations of VK1 and NADPH. Results represent average values obtained from triplicate incubations that were run for 45 min at 37°C. Standard deviation is denoted by error bars.