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Sample single-channel currents from cells expressing wild-type concatemeric γβα-βα GABA-A receptors. The cells were exposed to 20, 100, 500, or 2000 μM GABA. The increase in agonist concentration results in an increase in cluster open probability. At 20 μM GABA, only isolated openings and short bursts were observed. Channel openings are shown as downward deflections. The putative clusters at 100 to 2000 μM GABA are shown with lines above the current traces.
