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. 2009 Mar 16;75(6):1400–1411. doi: 10.1124/mol.108.054510

TABLE 1.

Open times for wild-type concatemeric γβα-βα receptors

Receptors were activated by 20 to 5000 μM GABA. The table gives the mean durations (OT1-3) and prevalence (fraction OT1-3) for the three open time components and the number of patches for each condition. The data are presented as mean ± S.D.

[GABA] OT1 Fraction OT1 OT2 Fraction OT2 OT3 Fraction OT3 n
ms ms ms
20 μM 0.45 ± 0.09 0.30 ± 0.03 4.9 ± 0.5 0.57 ± 0.09 11.8 ± 1.6 0.14 ± 0.12 3
50 μM 0.27 ± 0.13 0.24 ± 0.11 3.9 ± 0.6 0.58 ± 0.15 12.6 ± 4.0 0.18 ± 0.11 4
100 μM 0.34 ± 0.20 0.20 ± 0.08 3.9 ± 1.0 0.62 ± 0.24 11.0 ± 2.2 0.17 ± 0.16 4
200 μM 0.23 ± 0.16 0.16 ± 0.13 4.1 ± 1.4 0.53 ± 0.29 9.6 ± 3.7 0.30 ± 0.16 3
500 μM 0.27 ± 0.10 0.10 ± 0.01 4.6 ± 0.8 0.64 ± 0.16 11.1 ± 4.2 0.26 ± 0.15 3
1000 μM 0.40 ± 0.14 0.16 ± 0.06 3.8 ± 0.6 0.73 ± 0.10 10.2 ± 2.4 0.11 ± 0.10 5
2000 μM 0.38 ± 0.07 0.17 ± 0.03 3.5 ± 0.4 0.67 ± 0.17 10.4 ± 2.4 0.16 ± 0.15 3
5000 μM 0.42 ± 0.17 0.16 ± 0.13 2.8 ± 0.7 0.67 ± 0.18 6.5 ± 1.9 0.17 ± 0.11 5