Table 1.

Inhibition of TaqNP and TaqN nucleases by anti-TaqNP antibodies

Antibody	Inhibition		Subunit
	DNA polymerization	DNA binding
No effect
4-4	−	−	N
4-1	−	++	N
4-5	−	−	P
4-11	−	−	N
4-14	−	−	P
Inhibit TaqNP
4-9	+	++	P
4-3	+	±	P
TP-2	+	±	P
TP-7	+	++	P
TP-9	+	±	P
Inhibit TaqNP and TaqN
TP-8	+	−	N
4-15	−	++	N
4-17	−	++	N
Inhibit TaqN
3-1	+	±	N
TP-5	+	−	N
Stimulate TaqNP*
4-8	−	−	P
4-13	−	−	P
TP-3	+	±	P
TP-4	+	−	P
TP-6	±	−	P
3-5	−	±	P
3-7	−	−	P

Nuclease assays were as described in Fig. 5, using D16 substrate with gap 4 primer (see Fig. 1) except for stimulation of TaqNP, which used D6 substrate with gap 4 primer. Data on inhibition of DNA polymerization and DNA-binding and subunit recognition are from ref. 23.