CYP1 mRNA levels after 18 days of continuous oral BaP (125 mg/kg/day). The
CYP1A1 mRNA levels from cornoil treated WT 1A1 mice in each tissue
were set as “1.0 control,” and relative mRNA levels are expressed
as -fold increases on a logarithmic scale; note values on the y-axis
vary over a >1000-fold range. ND, nondetectable. The mRNA levels are
expressed relative to β-actin mRNA levels; thus, values within a tissue,
but not between tissues, can be compared. Data are reported as means ±
S.E.M. of four mice per group. Designation of mouse lines is the same as that
in Fig. 2. *,
P < 0.05, compared with mRNA levels for that gene in BaP-treated
WT 1A1 mice. †, P < 0.05, compared with mRNA
levels for that gene in corn oiltreated WT 1A1 mice.