Figure 1.
Cholesterol-independent effects of statins. Plus sign = enhanced/activated; minus sign = inhibited; AT1 = angiotensin 1; ET-1 = endothelin 1; hs-CRP = high-sensitivity C-reactive protein; MMPs = matrix metalloproteinases; NO = nitric oxide; PAI-1 = plasminogen activator inhibitor-1; ROS = reactive oxygen species; SMC = smooth muscle cell; TF = tissue factor; t-PA = tissue-type plasminogen activator; TXA2 = thromboxane A2. (Adapted with permission from Arterioscler Thromb Vasc Biol.)4
