Table 3. Risk of lung cancer-specific death in proband's relative (child, sibling, spouse) depending on proband survival.

Pairs of relatives	Survival in probanda	Number of relatives to proband	Number of deaths in relative to proband	Risk of lung cancer related death in proband's relative
				Adjusteda	Trend test	Adjustedc	Trend test
				HR (95% CI)	p valuesb	HR (95% CI)	p valuesb
Parentd-Childe					0.05		0.04
	Good	109	67	0.73 (0.52–1.00)		0.71 (0.51–0.99)
	Expected	221	157	0.87 (0.68–1.16)		0.86 (0.65–1.13)
	Poor	109	83	1.0 ref.		1.0 ref.
Sibling-Siblinge					0.02		0.05
	Good	15	4	0.24 (0.072–0.81)		0.14 (0.030–0.65)
	Expected	32	25	1.42 (0.66–3.05)		1.26 (0.48–3.27)
	Poor	16	10	1.0 ref.		1.0 ref.
Spouse-Spoused					0.32		0.26
	Good	131	97	0.87 (0.66–1.15)		0.85 (0.64–1.13)
	Expected	262	196	0.91 (0.71–1.15)		0.90 (0.70–1.15)
	Poor	132	102	1.0 ref.		1.0 ref.

^aMultivariate proportional hazard (Cox) model adjusted for calendar year of diagnosis and age at diagnosis.

^bOne degree of freedom.

^cMultivariate proportional hazard (Cox) model adjusted for calendar year, age and place of diagnosis, socioeconomic status, tumour histology and gender.

^dParents (Spouses) diagnosed between January 1961 and December 2001.

^eChildren (siblings) diagnosed between January 1991 and December 2001.