TABLE 2.

MCF-7 and MCF-7/DX1 cytotoxicity IC₅₀ values for paclitaxel with various concentrations of coadministered Q2

IC₅₀ values reported as the concentration leading to 50% of cell viability. Cellular viability as measured by the MTT assay after a 72-h incubation with the specified compounds. IC₅₀ values reported as the concentration leading to 50% of cell viability.

	Paclitaxel in the Presence of
	0 μM Q2	1 μM Q2	2 μM Q2	4 μM Q2	6 μM Q2
MCF-7	3.1 ± 1.0 nM	N.A.	N.A.	N.A.	N.A.
MCF-7/DX1	9.03 ± 0.03 μM	6.3 ± 0.2 μM	2.0 ± 0.3 μM	3.0 ± 1.1 nM	4.0 ± 1.0 nM

N.A., not available.