TABLE 3.
Rates and hazard ratios for cardiovascular disease events by CRF groups in men, Aerobics Center Longitudinal Study, Dallas, Texas, 1971-2004
| Events | Rate† | HR‡ | 95% CI‡ | HR§ | 95% CI§ | |
|---|---|---|---|---|---|---|
| Total CVD | ||||||
| Low CRF | 345 | 107.9 | 1.00 | Referent | 1.00 | Referent |
| Moderate CRF | 664 | 75.2 | 0.82 | 0.72, 0.94 | 0.89 | 0.78, 1.02 |
| High CRF | 503 | 50.3 | 0.61 | 0.53, 0.71 | 0.75 | 0.64, 0.87 |
| p linear trend | <0.001 | <0.001 | <0.001 | |||
| Coronary heart disease | ||||||
| Low CRF | 289 | 88.9 | 1.00 | Referent | 1.00 | Referent |
| Moderate CRF | 533 | 60.5 | 0.81 | 0.70, 0.94 | 0.89 | 0.77, 1.03 |
| High CRF | 400 | 40.3 | 0.61 | 0.52, 0.71 | 0.76 | 0.64, 0.90 |
| p linear trend | <0.001 | <0.001 | 0.001 | |||
| Myocardial infarction | ||||||
| Low CRF | 123 | 35.6 | 1.00 | Referent | 1.00 | Referent |
| Moderate CRF | 212 | 24.1 | 0.80 | 0.64, 1.01 | 0.87 | 0.69, 1.09 |
| High CRF | 154 | 16.2 | 0.60 | 0.46, 0.77 | 0.73 | 0.56, 0.96 |
| p linear trend | <0.001 | <0.001 | 0.02 | |||
| Stroke | ||||||
| Low CRF | 56 | 19.0 | 1.00 | Referent | 1.00 | Referent |
| Moderate CRF | 131 | 14.8 | 0.86 | 0.63, 1.18 | 0.90 | 0.65, 1.24 |
| High CRF | 103 | 10.0 | 0.63 | 0.45, 0.89 | 0.71 | 0.49, 1.01 |
| p linear trend | <0.001 | 0.005 | 0.04 | |||
HR, Hazard ratio; CI, Confidence interval; CVD, cardiovascular disease; CRF, cardiorespiratory fitness.
There were 66,887, 70,222, and 78,872 man-years of follow-up in the low, moderate, and high fitness groups, respectively.
Rate per 10,000 person-years adjusted for age and examination year.
Adjusted for the above plus current smoking (yes or not), alcohol intake (≥5 drinks/wk, or not), family history of CVD (present or not), and abnormal exercise electrocardiogram responses (present or not).
Adjusted for the above plus body mass index (<25 or ≥25 kg/m2), hypertension, diabetes, or dyslipidemia (present or not for each).