Table 3.
Hospitalizations by causes in geriatric heart failure patients before and after matching by propensity scores for NYHA class III–IV
Cause for hospitalization* | NYHA I–II (N=1010)
|
NYHA III–IV (N=1010)
|
Absolute difference† (per 10,000 person-year of follow up) | Hazard ratio (95% confidence interval)‡ | P value |
---|---|---|---|---|---|
Hospitalization Events/total follow-up years (Rate per 10,000 person-years of follow up) | |||||
Before matching | |||||
All-cause | 682/1763 (3868) | 736/1418 (5190) | + 1322 | 1.30 (1.17–1.44) | <0.0001 |
Cardiovascular | 501/2113 (2371) | 588/1753 (3354) | + 983 | 1.37 (1.21–1.54) | <0.0001 |
Worsening heart failure | 263/2609 (1008) | 381/2176 (1751) | + 743 | 1.68 (1.43–1.96) | <0.0001 |
Number of total hospitalizations | 10533 | 16262 | + 5729 | ||
After matching | |||||
All-cause | 723/1553 (4656) | 736/1418 (5190) | + 534 | 1.10 (0.96–1.25) | 0.165 |
Cardiovascular | 557/1899 (2933) | 588/1753 (3354) | + 421 | 1.11 (0.96–1.29) | 0.150 |
Worsening heart failure | 363/303 (1576) | 381/2176 (1751) | + 175 | 1.09 (0.92–1.30) | 0.330 |
Number of total hospitalizations | 13799 | 16262 | + 2463 |
Data shown include the first hospitalization of each patient due to each cause.
Absolute differences were calculated by subtracting the percentage of patients hospitalized in the placebo group from the percentage of patients hospitalized in the digoxin group (before values were rounded).
Hazard ratios and confidence intervals (CI) were estimated from a Cox proportional-hazards models that used the first hospitalization of each patient for each reason