Table 3.
Crude and adjusted ORs (95% CI) of breast cancer by ADIPOQ and ADIPOR1 SNP genotypes
| SNPs | Crude OR | OR adjusting for age* , SNPs†, and race |
|
|---|---|---|---|
| rs266729 | GG | 1.00 | 1.00 |
| GC | 1.15 (0.76–1.74) | 1.05 (0.65–1.68) | |
| CC | 1.00 (0.67–1.50) | 0.88 (0.55–1.42) | |
| rs822395 | CC | 1.00 | 1.00 |
| AC | 1.17 (0.85–1.61) | 1.03 (0.68–1.55) | |
| AA | 1.17 (0.85–1.61) | 0.97 (0.61–1.54) | |
| Rs822396 | GG | 1.00 | 1.00 |
| GA | 1.55 (0.85–2.81) | 1.39 (0.67–2.87) | |
| AA | 1.53 (0.86–2.73) | 1.65 (0.77–3.53) | |
| rs2241766 | TT | 1.00 | 1.00 |
| TG | 0.66 (0.52–0.83)‡ | 0.61 (0.46–0.80)‡ | |
| GG | 0.72 (0.41–1.28) | 0.63 (0.32–1.25) | |
| rs1501299 | TT | 1.00 | 1.00 |
| TG | 1.46 (0.99–2.16) | 1.59 (1.03–2.48)§ | |
| GG | 1.43 (0.98–2.09) | 1.80 (1.14–2.85)§ | |
| rs2232853 | CC | 1.00 | 1.00 |
| CT | 1.47 (1.18–1.84)‡ | 1.67 (1.23–2.26)‖ | |
| TT | 0.81 (0.54–1.21) | 1.02 (0.60–1.76) | |
| rs12733285 | TT | 1.00 | 1.00 |
| TC | 1.18 (0.87–1.60) | 1.16 (0.78–1.73) | |
| CC | 1.11 (0.82–1.50) | 1.19 (0.77–1.85) | |
| rs1342387 | AA | 1.00 | 1.00 |
| AG | 0.90 (0.71–1.14) | 0.74 (0.53–1.03) | |
| GG | 0.84 (0.63–1.12) | 0.72 (0.46–1.12) | |
| rs7539542 | GG | 1.00 | 1.00 |
| GC | 0.81 (0.60–1.09) | 0.59 (0.36–0.98)§ | |
| CC | 0.84 (0.62–1.14) | 0.51 (0.28–0.92)§ | |
| rs10920531 | CC | 1.00 | 1.00 |
| CA | 0.88 (0.71–1.10) | 0.80 (0.56–1.14) | |
| AA | 0.89 (0.67–1.20) | 0.61 (0.35–1.06) |
Age adjustment was done by using categorical age groups (age >50 y and age <50 y).
Adjustment for SNPs was only done with SNPs from the same gene.
P < 0.001 without Bonferroni adjustment; P < 0.005 with Bonferroni adjustment.
P < 0.05 without Bonferroni adjustment; 0.05 < P < 0.10 with Bonferroni adjustment.
P < 0.01 Without Bonferroni ajustment; P < 0.05 with Bonferroni adjustment.