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Epithelial proliferation and apoptosis. BrDU incorporation in crypts was significantly increased in neointestinal crypts containing VEGF-loaded microspheres demonstrating increased proliferation. (n=5/group) (*p<0.05) Apoptosis measured by TUNEL staining showed no difference in programmed cell death between neointestinal cysts containing empty or VEGF-loaded microspheres. (n=5/group)
