Table 2.
Pulmonary blood volume (PBV), pulmonary blood flow (PBF), and mean transit time (MTT) averages, ±1 standard deviations, and coefficients of variation (Cv) of all injection volumes (50, 100, and 150µL pairs) for each ROI in Figure 7. The PBV, PBF, and MTT values were calculated using SVD of the time density curves in Figure 8. The pulmonary artery root was used as the arterial input function. Note how the coefficients of variation are all < 22%, with most being between 0.04–8.2%. In addition, the change in MTTs between the same ROIs for each injection volume was statistically insignificant (all p-values ≥ 0.816)
| PBV, PBF, and MTT values: avg ± 1 SD |
PBV (µL) | Cv (%) | PBF (µL/100µL/sec) |
Cv (%) | MTT (sec) | Cv (%) |
|---|---|---|---|---|---|---|
| 50µL inj. | ||||||
| Left pul. artery | 0.86±0.012 | 1.5 | 1.88±0.12 | 6.4 | 0.47±0.030 | 6.4 |
| R. lung tissue | 1.01±0.078 | 7.7 | 1.09±0.05 | 4.8 | 0.96±0.025 | 2.6 |
| Left ventricle | 1.61±0.89 | 5.5 | 1.58±0.0.13 | 7.9 | 1.04±0.140 | 13.5 |
| Aorta | 0.71±0.034 | 4.7 | 0.77±0.13 | 17.1 | 0.95±0.207 | 21.9 |
| 100µL inj. | ||||||
| Left pul. artery | 1.00±0.005 | 0.5 | 2.36±0.042 | 1.8 | 0.44±0.014 | 3.3 |
| R. lung tissue | 1.02±0.003 | 0.3 | 1.20±0.022 | 1.9 | 0.89±0.010 | 1.2 |
| Left ventricle | 1.82±0.110 | 6.0 | 1.84±0.032 | 1.7 | 1.00±0.079 | 7.9 |
| Aorta | 0.69±0.022 | 3.1 | 0.76±0.0002 | 0.04 | 0.92±0.029 | 3.1 |
| 150µL inj. | ||||||
| Left pul. artery | 1.05±0.025 | 2.4 | 2.38±0.196 | 8.2 | 0.46±0.053 | 11.5 |
| R. lung tissue | 1.02±0.013 | 1.2 | 1.22±0.032 | 2.6 | 0.87±0.048 | 5.5 |
| Left ventricle | 1.85±0.004 | 0.2 | 1.76±0.017 | 0.9 | 1.06±0.013 | 1.2 |
| Aorta | 0.69±0.017 | 2.5 | 0.83±0.043 | 5.2 | 0.84±0.022 | 2.6 |