Fig. 2.

Amino acid sequence of starfish GSS. (A) Comparison of the heterodimeric structure of starfish GSS with those of various representative members of the insulin superfamily. The cysteine bridges are shown in red. (B) Coding DNA sequence and predicted amino acid sequences of GSS. Sequences of A and B chains are shown in green and blue boxes, respectively. Characters shown in red boldface indicate basic dipeptides that are the sites of proteolytic cleavage. Inverted triangle shows the deduced cleavage site of the signal peptide.