Table 1.

Scoring system used to grade histological severity of colitis in mice treated with DSS

	0	1	2	3	4
A) Epithelium	Intact	Erosion	Ulcer	Multiple ulcers	Segmental necrosis
B) Density of leukocyte infiltration	None	Slight	Marked	Strong	Massive
C) Depth of infiltration	None	Subepithelial	Confined to the lamina propria	Muscularis involved	Serosa involved

DSS, dextran sulfate sodium. *An overall score was calculated as follows: (A + B + C)/3.