Table 2.

Sleep-wake fragmentation and bout analysis

	wt	db/db	P
Stage Shifts
Light	329.3±15.4	430.5±26.9	§
Dark	201.3±18.1	272.9±11.5	§
24 h	530.6±29.2	703.4±24.6	§
Arousals
Light	85.4±5.1	109.1±4.7	†
Dark	48.1±5.1	59.6±2.8	‡
24 h	132.4±8.8	167.6±6.1	†
No. W bouts
Light	61.1±2.9	91.3±4.7	§
Dark	48.1±4.2	70.3±3.9	§
24 h	108.8±6.1	161.2±7.6	§
No. NREM bouts
Light	140.3±6.2	186.1±5.6	§
Dark	87.3±8.1	119.4±5.5	†
24 h	227.1±12.3	305.0±9.9	§
No. REM bouts
Light	36.5±2.2	29.2±1.8	*
Dark	11.2±1.0	14.5±0.8	*
24 h	47.6±2.1	43.7±2.1
Dur. W bouts
Light	3.9±0.3	2.5±0.1	§
Dark	11.6±1.3	6.5±0.5	†
24 h	7.0±0.5	4.2±0.2	§
Dur. NREM bouts
Light	3.1±0.1	2.4±0.1	§
Dark	2.5±0.2	2.2±0.1
24 h	2.9±0.1	2.3±0.1	§
Dur. REM bouts
Light	1.4±0.04	1.3±0.05
Dark	1.3±0.07	1.2±0.04
24 h	1.3±0.04	1.2±0.04

Amount of sleep fragmentation was quantified in wild-type (wt, n =13) and db/db (n =13) mice across the 24-h recording period and for individual 12-h-light and 12-h-dark periods. Groups were compared for stage shifts, brief arousals from sleep, the number (No.) of sleep and wake bouts and the average duration (Dur., minutes) of individual sleep and wake bouts. Values represent group means ± SE. Genotype comparisons (

^‡P < 0.07,

^*P < 0.05,

^†P < 0.01,

^§P < 0.001).