Fig. 2.
Effect of phenylephrine (Phe; 10−5 M) on vasoconstriction and [Ca2+]i in mesenteric microvessels of Norm-Preg and RUPP rats. Simultaneous measurements of Phe-induced changes in diameter and 340/380 fluorescence ratio were recorded in isolated microvessels from Norm-Preg (A, C) and RUPP rat (B, D). Bar graphs represent means ± SE of vasoconstriction and [Ca2+]i measurements in 10 microvessels of Norm-Preg (E, G) and 9 microvessels of RUPP rats (F, H). *,†[Ca2+]i (340/380 ratio) measurements in RUPP rats are significantly different (P < 0.05) from corresponding measurements in Norm-Preg rats.