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The effect of chronic hypoxia on endothelium-derived NO production in rat PA. Carbachol-stimulated NO production was measured with NO electrode in control and chronically hypoxic PA and following pretreatment with 10 μM SB-203580. Results are expressed as means ± SE; n = 6 experiments. #P < 0.001 vs. control; *P < 0.01 vs. chronic hypoxia.
