Table 1.
Treatment | Group n* | Uninjured Artery, mm† | Injured Artery, mm† |
---|---|---|---|
Day 0 | 15, 12 | 1.87±0.04 | 1.95±0.06 |
Day 35 Saline‡ | 3, 3 | 1.99±0.02 | 2.08±0.08 |
LPS‡ | 2, 2 | 1.97±0.05 | 2.09±0.12 |
Cultured HA crystals‡ | 2, 3 | 2.01±0.20 | 2.07±0.12 |
Bovine NPs | 5, 5 | 2.21±0.05 | 2.17±0.10 |
Human NPs‡ | 4, 2§ | 2.22±0.06 | 2.27±0.09 |
Number of individual animals in which uninjured and injured arteries were imaged. Not all arteries could be imaged from all rabbits at both time points.
Values are means ± SE of lumen diameter.
Ultrasound images were not obtained on all animals in this group.
Data from 2 arteries that remained patent; 3 injured arteries from animals in this group occluded within 1–3 wk of the injection. HA, hydroxyapatite; NP, nanoparticle.