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Recordings from an isolated rat ventricular myocyte at 1-Hz stimulation with the stretch-activated channel conductance (GSAC) applied from 6.5 through 11.5 s at various levels. Early afterdepolarization (EAD) was not induced at any levels of GSAC. However, a transient activity was observed at a high GSAC (7 nS), but failed to sustain, and the cell became refractory to direct stimulation.
