Table 2.

Percent change in AP parameters with increased stimulation frequency

	1 Hz, GSAC = 0 nS	%Change From GSAC = 0 nS
1 Hz, GSAC = 2 nS		3 Hz, GSAC = 0 nS	3 Hz, GSAC = 2 nS
Control solution
RMP, mV	−78.6±0.6	−2.7±0.4*	−4.3±0.8	−23.0±4.1*
APD30, ms	3.9±0.7	−4.5±5.1	4.0±3.3	−1.1±1.5
APD50, ms	8.5±2.1	−3.9±2.5	2.7±2.8	0.9±1.3
APD90, ms	28.6±2.6	6.2±5.6*	2.2±2.3	33.6±14.1*
APA, mV	98±25	−12.6±17	−0.4±1.2	−0.6±2.0
10-min Exposure to 100 μM H2O2
RMP, mV	−79.5±0.5	−4.5±0.6†	−14.7±7.8	−19.6±5.4†
APD30, ms	3.8±0.9	−1.8±1.4	−1.5±2.0	−21±19.8
APD50, ms	8.3±0.3	−4.9±6.2	−2.5±1.9	6.6±4.8
APD90, ms	33.3±6.2	2.3±2.4	4.9±4.6	24±4.2†
APA, mV	103.0±3.8	−8.7±6.1	11.5±12.3	−1.1±2.5

Values are means ± SE; n = 12.

^*P < 0.05 compared with 1 Hz for control solution with G_SAC = 0 nS.

^†P < 0.05 compared with 1 Hz for 100 μM H₂O₂ with G_SAC = 0 nS.