Fig. 7.
PM2.5 exposure enhances ANG II-induced cardiac collagen deposition. A and B: representative micrographs (A) and summary of data (B) analyzed by Masson's trichrome staining. C and D: representative micrographs (C) and summary of data (D) analyzed by picrosirius red staining. E–H: mRNA expression of cardiac collagen deposition-related genes analyzed by real-time RT-PCR and expressed as fold increases over GAPDH. TGF, transforming growth factor. n = 6 animals/group. *P < 0.05 vs. the same exposure in animals infused with vehicle; #P < 0.05 vs. FA exposure in animals infused with the same drug; $P < 0.05 vs. the same exposure in animals infused with ANG II.