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Effects of NO donors on DOX-induced mitochondrial superoxide formation in vitro. Shown are the effects of NO donors in both short-term (4 h; A) and long-term (16 h; B) DOX-induced mitochondrial superoxide formation. *P < 0.001 vs. vehicle; #P < 0.001 vs. the corresponding DOX concentration. n = 6 per group.
