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. 2009 Apr 27;9:25. doi: 10.1186/1472-6807-9-25

Table 1.

Number of over-exposed residues with their exposed surface area (ASA) greater than the Ala-X-Ala extended state ASA (ESA).

Res. Freq
(%)
Res. Freq
(%)
Res. Freq
(%)
Res. Freq
(%)
A 0.66 G 2.35 M 0.36 S 1.91
C 0.10 H 0.62 N 3.31 T 0.94
D 3.45 I 0.05 P 0.45 V 0.15
E 2.54 K 0.76 Q 1.22 W 0.11
F 0.15 L 0.09 R 0.88 Y 0.20

Typically, polar and charged residues have a significant number of such cases.