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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Immunol. 2009 Jun 1;182(11):6690–6696. doi: 10.4049/jimmunol.0900524

Figure 4. Role of TIRAP in P. gingivalis fimbria-induced proadhesive or proinflammatory activities in mouse macrophages.

Figure 4

Mouse macrophages were pretreated for 1h with 10 μM of a cell-permeable TIRAP inhibitory peptide or inactive control. The cells were subsequently left unstimulated or were stimulated with P. gingivalis fimbriae (1 μg/ml) and assayed for sICAM-1 binding or induction of IL-6 release. Data are means ± SD (n = 3) from one of two independent experiments that yielded consistent findings. Asterisks indicate statistically significant (p < 0.05) differences compared to medium-treated (no peptide) controls.