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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: J Immunol. 2009 Jun 1;182(11):6670–6681. doi: 10.4049/jimmunol.0803683

Figure 7.

Figure 7

Non-B cell APCs can process and present immune-complexed HBcAg to naïve, CD4+ T cells but not free HBcAg. Either free HBcAg183 (1 μg/ml) or HBcAg183- complexed to HBcAg-specific Mabs (3105 + 3120) (2 μg/ml) were added to 7/16-5 TCR-Tg spleen cells (B cell+) or 7/16-5/BKO spleen cells (B cell) and CD4+ T cell activation was determined by IL-2 (day 2) and IFNγ (day 4) cytokine production in culture supernatants measured by ELISA. Values are express as pg/ml. The results are representative of 3 separate experiments.