Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Endotoxin contamination of HBcAg does not enhance anti-HBc antibody production in vivo. Groups of 3 LPS-sensitive (C3H.HeSnJ) or LPS-insensitive (C3H.HeJ) mice were immunized with either a highly (LPS+) HBcAg149 preparation (10 ng/ml) or an HBcAg149 preparation free of LPS contamination (LPS−). Mice were immunized i.p. with 10 μg of HBcAg149 in saline and 5 weeks later serum anti-HBc IgG isotypes were measured by ELISA.
