TABLE 2.
Two-point HLOD-scores obtained from linkage analysis of constitutional delay of growth and puberty exceeding 2, and corresponding multipoint HLOD-scores in the fine mapping analysis of chromosome 2p13-2q13.
| Locus | Position (cM) |
Two-point analysis | Multipoint analysis | ||||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| HLOD | α | Information | HLOD | α | Information | ||
| D2S388 | 110.1 | 2.15 | 0.36 | 0.62 | 1.99 | 0.26 | 0.98 |
| D2S2159 | 112.6 | 2.12 | 0.33 | 0.73 | 2.61 | 0.33 | 0.99 |
| D2S2209 | 114.8 | 2.77 | 0.44 | 0.71 | 2.70 | 0.34 | 0.99 |
| D2S2264 | 116.1 | 2.17 | 0.41 | 0.71 | 3.95 | 0.41 | 0.99 |
| D2S2364 | 118.3 | 3.70 | 0.62 | 0.57 | 4.02 | 0.39 | 0.97 |
| D2S2229 | 119.0 | 3.38 | 0.43 | 0.73 | 4.44 | 0.41 | 0.99 |
| D2S293 | 119.8 | 2.87 | 0.40 | 0.76 | 3.01 | 0.37 | 0.99 |