TABLE 3.
Haplotypes on chromosome 2q11-2q12 co-segregating with constitutional delay of growth and puberty in 5 families from central and eastern Finland. LOD-score is obtained by multipoint analysis at marker position D2S2229. Family_5 shared 2 alleles throughout the region.
| Family | D2S2209 | D2S2264 | D2S373 | D2S2364 | D2S2229 | D2S293 | LOD- score |
|---|---|---|---|---|---|---|---|
| Family_1 | 190 | 251 | 237 | 101 | 181 | 178 | 2.07 |
| Family_2 | X | 255 | 237 | 99 | 181 | X | 1.77 |
| Family_3 | 198 | 233 | 223 | 99 | 191 | 176 | 0.29 |
| Family_4 | 192 | 251 | 237 | 95 | 181 | 174 | 0.29 |
| Family_5/1 | 198 | 243 | 223 | 95 | 205 | 174 | 0.16 |
| Family_5/2 | 202 | 253 | 245 | 99 | 189 | 182 |