TABLE IV.
(A) ADHD Association with Haplotype 2 (SNPs 3 and 4) in the Finnish Sample (n=310), (B) PTSD Association With Haplotype 1 (SNPs 1 and 2) in LA Caucasian Parent Sample (n=320)*
| Estimate haplotype frequencies |
||||
|---|---|---|---|---|
| (A) Phenotype | C-G2 | C-T2 | T-G2 | T-T2 |
| ADHD (n=159) | 0.19 | 0.37 | 0.43 | 0.01 |
| Not ADHD (n=151) | 0.11 | 0.39 | 0.49 | 0.01 |
| 7.10 | 0.15 | 1.95 | 0.33 | |
| P-value | 0.008 | 0.50 | 0.16 | 0.56 |
| Estimate haplotype frequencies |
|||
|---|---|---|---|
| (B) Phenotype | C-A1 | C-G1 | T-A1 |
| PTSD (n=22) | 0.65 | 0.12 | 0.23 |
| Not PTSD (n=280) | 0.50 | 0.29 | 0.21 |
| 4.21 | 6.53 | 0.08 | |
| P-value | 0.04 | 0.01 | 0.78 |
, P-value=0.05 global analysis of association
Variation in sample sizes reflects cases that were missing either genotype data or specific diagnoses were uknown
(B) , P-value=0.03 global analysis of association.