Table 3.

Results of the Bivariate Linkage Analysis

Skeletal sites	LOD	LODE*	p	p1†	p0†	Location	Nearest marker
Femoral neck	3.65‡	3.11	7.64 E−05	0.07	0.19	20q11.23 (57)	GATA42A03
	2.96	2.46	3.79 E−04	—	—	Xp11.4 (58)	GATG011
Lumbar spine	4.89§	4.30	4.25 E−06	—	—	Xq27.3 (166)	TATC043
	3.39	2.86	1.41 E−04	0.13	0.07	12p11.23 (39)	GATA6C01
	2.94	2.44	3.98 E−04	0.50	0.02	17q21.2 (64)	GATA25A04
Ultradistal-forearm	3.54‡§	3.01	9.76 E−05	0.001	0.002	5q23.1 (127)	GATA62A04
	3.45§	2.92	1.22 E−04	0.001	0.17	7p15.1 (35)	GATA41G07
	2.93§	2.43	4.08 E−04	—	—	Xq27.3 (166)	TATC043
	2.92	2.42	4.19 E−04	0.13	0.47	12p11.23 (39)	GATA6C01

Here we only present the highest LOD scores in Figs. 1 and 2.

* LOD_E indicates the equivalent LOD scores comparable to traditional univariate ones.

^† p ₁ and p ₀ indicate the probabilities of complete pleiotropy and complete coincident linkage, respectively. The concordant p ₁ and p ₀ are shown in bold italics, which means one of them is <0.1 and the other is >0.1.

^‡ The locus linked to bone size in our previous univariate linkage study.(17)

^§ The locus linked to BMD in our previous univariate linkage study.(16)

—, pleiotropic tests on X chromosome are not supported by the current version of SOLAR.