Table 1.
Number of Individuals in Phase I and Phase II of the Study and the Total Number of Familial Cases
| Phase I |
Phase II |
Familial Casesa | |||
|---|---|---|---|---|---|
| Female | Male | Female | Male | ||
| Affected | 78 (32) | 89 (30) | 65 (4) | 84 (14) | 258 |
| Bipolar spectrum disorderb | 59 (29) | 68 (24) | 50 (4) | 50 (9) | 173 |
| Psychotic disorderc | 66 (27) | 65 (25) | 51 (4) | 69 (12) | 212 |
| In both categoriesd | 47 (24) | 44 (19) | 36 (4) | 35 (7) | 127 |
| Other mental disordere | 22 (14) | 12 (8) | 5 (2) | 7 (3) | 45 |
| Unaffected | 92 (29) | 69 (21) | 116 (1) | 84 (1) | 241 |
| Total Genotyped | 192 (75) | 170 (59) | 186 (7) | 175 (18) | 544 |
The number of neuropsychologically tested individuals is shown in parentheses.
BPD-I, bipolar disorder type I; BPD-II, bipolar disorder type II; NOS, not otherwise specified.
The familial cases are from 118 families with more than one affected individual.
Contains BPD-I (n = 214), BPD-II (n = 5), bipolar disorder NOS (n = 6), and cyclothymia (n = 2) cases.
Contains BPD-I with intermittent psychotic features (n = 162), psychotic depression (n = 15), schizophrenia (n = 14), schizoaffective disorder (n = 51), and psychotic NOS (n = 9). Numbers are from the whole sample.
Overlap between bipolar spectrum and psychotic disorder categories.
Contains depression, alcohol-, related disorders and delusional, adjustment, dysthymic, and panic disorders.