Table 4.
The Effect of DAOA Variant rs2391191 and COMT Variant rs165599 on Visuospatial Ability (Block Design), Showing Mean Values of Block Design Test in Cross Table of DAOA rs2391191 and COMT rs165599 Genotypes in All Individuals and in Psychotic and Nonpsychotic Groups
| COMT Variant rs165599 |
DAOA Variant rs2391191 |
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| All |
Psychotic |
Nonpsychotic |
|||||||||||||
| AA | AG | GG | Mean (n) | p value | AA | AG | GG | Mean (n) | p value | AA | AG | GG | Mean (n) | p value | |
| CC | 30.6 (7) | 38.1 (8) | 28.2 (5) | 34.1 (22) | .009 | 35.7 (3) | 40.5 (4) | 22.0 (1) | 33.2 (9) | .013 | 39.3 (4) | 35.8 (4) | 29.8 (4) | 34.8 (139) | .252 |
| CT | 32.2 (16) | 26.8 (28) | 23.3 (12) | 28.0 (61) | 34.8 (5) | 22.7 (12) | 23.3 (4) | 25.9 (22) | 30.8 (11) | 30.0 (16) | 23.4 (8) | 29.2 (39) | |||
| TT | 29.5 (20) | 28.1 (37) | 15.6 (16) | 25.7 (73) | 23.1 (8) | 23.9 (16) | 14.0 (11) | 20.9 (36) | 33.7 (12) | 31.2 (21) | 19.0 (5) | 30.4 (37) | |||
| Mean (n) | 31.8 (43) | 28.7 (73) | 20.3 (33) | 29.3 (16) | 25.7 (33) | 16.0 (15) | 33.3 (27) | 31.2 (40) | 23.9 (18) | ||||||
| p value | 2.3E-05 | .003 | .008 | ||||||||||||
The numbers of individuals that belong to a specific genotype group are in parentheses. The mean scores and the p values from one-way ANOVA are shown for each genotype group separately.
ANOVA, analysis of variance; COMT, catechol-O-methyl transferase; DAOA, d-amino acid oxidase activator.