TABLE 2.

Down-regulation of α1 affects liver cholesterol content and plasma lipid profile

	α1+/+	α1+/-
Cholesterol/unit of protein (% of WT)	100 ± 2	115 ± 5a
Plasma cholesterol (mg/dl)	120 ± 11.1	81.7 ± 25.8b

^ap < 0.05 compared to α1^+/+.

^bp < 0.01 compared to α1^+/+.