TABLE 1.

Aroclor 1254 induces preterm birth in C57BL/6 IL-10^−/− mice

All of the values are expressed as the means ± S.D.

Matings	Treatmenta	Preterm birthb	Litter size	Placental weightc	Fetal weightc
C57BL/6 × C57BL/6	Vehicle	0/8d	10.0 ± 0.9	93.5 ± 7.5	141.4 ± 16.7
	A-1254	0/9	8.3 ± 1.0	90.9 ± 5.3	136.7 ± 15.7
C57BL/6 IL-10−/− × C57BL/6 IL-10−/−	Vehicle	0/7	9.0 ± 1.0	92.9 ± 7.7	136.2 ± 17.1
	A-1254	13/13	4.1 ± 1.0e	81.1 ± 6.1e	119.5 ± 8.9e

^aIntraperitoneal injection of 100 μl of vehicle (corn oil) or 500 μg of A-1254/mouse from gd 4 to 12.

^bBirth on gd 17 ± 0.5.

^cWeight in mg on gd 13.

^dThe numbers refer to the number of vaginal plug-positive females.

^ep <0.05 according to Student's t test.