TABLE 1.
List of significant negative interactions (synthetic sick) observed after crossing Δtxl1 to a set of 2,295 deletion strains
The list is arranged in descending S-score (or E-MAP score) (28), and a cut-off of −3 was used. Where known, the encoded S. pombe and corresponding S. cerevisiae homologs are listed.
| S. pombe open reading frame | S. pombe protein | S. cerevisiae homolog | E-MAP score |
|---|---|---|---|
| SPAC17C9.13C | Cut8 | STS1 | −10.657017 |
| SPAC589.06C | PHO88 | −10.360266 | |
| SPBC27B12.11C | None | −9.167332 | |
| SPAC3H5.08C | YKL121W,YMR102C | −8.244299 | |
| SPBP8B7.28C | None | −7.264413 | |
| SPCC736.08 | Cbf11 | None | −6.651497 |
| SPAC8C9.11 | YGL220W | −5.66225 | |
| SPBC1734.12C | Alg12 | ALG12 | −5.216294 |
| SPAC8C9.12C | MRS3,MRS4 | −5.090238 | |
| SPBC1734.13 | Atp3 | ATP3 | −4.801525 |
| SPBC337.03 | RTT103 | −4.51371 | |
| SPCC594.06C | VAM7 | −4.089038 | |
| SPAC29B12.04 | Snz1 | SNZ3,SNZ1,SNZ2 | −3.9765 |
| SPBC1778.09 | None | −3.880673 | |
| SPBC337.11 | YIM1 | −3.450755 | |
| SPBC725.05C | NPP1,NPP2 | −3.245368 | |
| SPBC337.04 | Ppk27 | PRR1 | −3.224489 |
| SPBC1773.06C | None | −3.139316 | |
| SPBC12D12.06 | Srb11 | SSN8 | −3.123008 |