FIGURE 2.

Co-expression of Mesd facilitates single LRP6 β-propeller BP1, -2, and -4, but not BP3, folding and secretion. A, BHK570 cells were transiently transfected with cDNAs for BP1, -2, -3, or -4, with co-transfection of either vector pcDNA or Mesd. B, quantification of secretion efficiency from Western blot analyses. Results shown in this figure and subsequent figures are representative of three independent experiments.