Co-expression of Mesd facilitates single LRP6 β-propeller
BP1, -2, and -4, but not BP3, folding and secretion. A, BHK570
cells were transiently transfected with cDNAs for BP1, -2, -3, or -4, with
co-transfection of either vector pcDNA or Mesd. B, quantification of
secretion efficiency from Western blot analyses. Results shown in this figure
and subsequent figures are representative of three independent
experiments.