Table 3.
Between-group ANOVA differences in brain activation between controls and patients under the placebo condition for the contrast of time discrimination versus order judgement. (BA, Brodman area; N voxels, number of voxels. p-value for ANCOVAs at p<0.05 for voxel activation and p<0.006 for cluster activation.)
| brain region | BA | Tal. coordinates (x, y, z) | N voxels | cluster p-value |
|---|---|---|---|---|
| (a) controls>ADHD | ||||
| R+L orbitofrontal/inferior/mesial frontal/anterior cingulated/caudate | 47/11/45/10/32/24 | 15, 19, −18 | 453 | 0.002 |
| R inferior/medial frontal gyrusa | 44/46 | 25, 59, 15 | 42 | 0.04 |
| L anterior cingulate gyrusa | 32 | −3, 55, 20 | 20 | 0.05 |
| R cerebelluma | 12, −73, −35 | 72 | 0.03 | |
| (b) ADHD>controls | ||||
| L middle/superior temporal/occipital/cerebellum | 21/39/22/19/18 | −43, −44, −2 | 502 | 0.002 |
| R dorsomedial frontal/superior temporal/insula/hippocampus/putamen | 46/22/24/32 | 33, 26, 15 | 490 | 0.003 |
a
Clusters that were significant at a more lenient p-value of <0.05.