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. 2008 Oct 24;328(1):99–106. doi: 10.1124/jpet.108.145201

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Fig. 5. — Direct effects of cocaine on cultured H9C2 cardiomyocytes. A, cocaine-induced mean light unit(s). B, effect of propanolol on production with or with out cocaine (25 μM). C, effect of Nox2 siRNA on cocaine-induced production and Nox2 protein expression. α-Tubulin was used as loading control. *, p < 0.05 for indicated values versus control values in the same group. D, effect of Nox2 siRNA on cocaine-induced myocyte death. Arrow, nuclear fragmentation and TUNEL-positive nucleus.

Inline graphic — Direct effects of cocaine on cultured H9C2 cardiomyocytes. A, cocaine-induced mean light unit(s). B, effect of propanolol on production with or with out cocaine (25 μM). C, effect of Nox2 siRNA on cocaine-induced production and Nox2 protein expression. α-Tubulin was used as loading control. *, p < 0.05 for indicated values versus control values in the same group. D, effect of Nox2 siRNA on cocaine-induced myocyte death. Arrow, nuclear fragmentation and TUNEL-positive nucleus.