Fig. 2.

Spt and Ntl bind similar sites in vitro. (A,B) Representative gel shifts using recombinant Spt-GST (A) and Ntl-GST (B). (C,D) WebLogo (Crooks et al., 2004) binding site models based on the sequences of >70 bound oligos from the in vitro selection assays are shown for Spt-GST (C) and Ntl-GST (D) with the count matrices for the sequenced binding sites below. Regions of binding sites contained in the non-random primer region of the oligonucleotide were not counted, therefore some columns have fewer total counts.